Cheap flights from San Francisco to Santiago
The lowest fare found is €401. The cheapest month to fly is October.
Search live pricesSearch round-trip pricesLowest price by month
| October | €401 |
| November | €429 |
When is the cheapest time to fly from San Francisco to Santiago?
Fares are typically lowest in October, starting from €401.
Popular routes
- San Francisco → Buenos Aires
- San Francisco → Buenos Aires Aeroparque
- San Francisco → Quito
- San Francisco → Guayaquil
- San Francisco → Montevideo
- San Francisco → Asuncion
- San Francisco → Caracas
- San Francisco → Panama City
- San Francisco → San Jose CR
- San Francisco → Guatemala City
- San Francisco → San Salvador
- San Francisco → Atlanta
Prices updated 2026-09-24